Integrated bioreactor system and cell culture control, learning and monitoring process using the same

Abstract

The present invention concerns an integrated bioreactor system, which allows the optimization of the application of mechanical, electrical and magnetic stimuli, which can be varied in type and number, in cells placed in three-dimensional models. Real-time monitoring in the stimulation of different cells also optimizes the regeneration process of different types of tissues, such as bone, cartilage, nerve, heart tissue, among others. The present invention relates, in a first aspect, to an integrated bioreactor system and, in a second aspect, the invention relates to a process of controlling, learning and monitoring cell culture.

Technical Field

The areas of tissue engineering are the main target of this invention, although this system can be applied to the production of other biological species (bacteria, algae, fungi).

IPC

C12M1/12
C12M1/36
C12M3/04

Publication number

PT117309

Publication

WIPO

Publication date

June 29, 2021

DPI Status

Portuguese Patent PT117309 – Pending
European Patent EP21199958.6 – Pending

Inventors

Paula Cristina Rodrigues Pascoal Faria

Nuno Manuel Fernandes Alves

Carla Sofia Monteiro De Moura

João Pedro Almeida Meneses

Applicants

Polytechnic of Leiria

Contacts

otic@ipleiria.pt